Help explore ways to improve comfort and quality of life for individuals with cancer health related quality of life is increasingly used as an end point in clinical trials particularly in diseases with a poor prognosis such as metastatic cancer quality of life may be of major concern. Assessing quality of life in clinical trials by fayers and hays should play an important part in making quality of life concepts accessible to both clinicians and researchers the book provides an excellent overview on the state of the art and current issues in quality of life assessment and research. Maguire p 1986 using measures of psychological impact of disease to inform clinical practice in proceedings of the international workshop on quality of life assessment and cancer treatment v ventafridda fsam van dam r yancik m tamburini edsamsterdam excerpta medica 119 126 google scholar. There is a growing recognition in oncology of the importance of maintaining or improving patients quality of life qol throughout the disease course with this goal in mind many clinical trials in oncology now seek to evaluate qol end points. Quality of life assessment in clinical trials methodologic issues neil k aaronson phd the netherlands cancer institute amsterdam the netherlands abstract historically health related quality of life research has been carried out at a de scriptive level providing rich data regarding the impact of disease and treatment on the physical functional psychologic and social health of
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